Aloe Vera Clinical Studies

There are countless studies that illustrate the many impressive benefits that aloe vera can have on skin tissue. Here are just a few, including some written by Lexli founder and lead formulator, Dr. Ahmed Abdullah.

Aloe Vera Gel Effect on Skin and Pharmacological Properties.

Saleem A, Naureen I, Naeem M, Safoora Mura H, Maqsood S, Tasleem G. Scholars International Journal of Anatomy and Physiology. 2022 July;5(1):1-8.


Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe Vera, Aloe marlothii and Aloe ferox.

Fox LT, Gerber M, du Preez JL, du Plessis J, Hamman JH.
Journal of Pharmacy and Pharmacology. 2015 Jan;67(1):96-106.


Effects of Aloe vera on gap junctional intercellular communication and proliferation of human diabetic and nondiabetic skin fibroblasts.

Abdullah KM, Abdullah A, Johnson ML, Bilski JJ, Petry K, Redmer DA, Reynolds LP, Grazul-Bilska AT.
Journal of Alternative Complementary Medicine 2003 Oct;9(5):711-8.


The effects of aloe extract on nitric oxide and endothelin levels in deep-partial thickness burn wound tissue in rat.

Lv RL, Wu BY, Chen XD, Jiang Q.
Zhonghua Shao Za Zhi. 2006 Oct;22(5):362-5.


Influence of Aloe vera on collagen turnover in healing of dermal wounds in rats.

Chithra P, Sajithial GB, Chandrakasan G.
Indian Journal of Experimental Biology. 1998 Sep;36(9):896-901


Topical Application of Aloe vera Accelerated Wound Healing, Modeling, and Remodeling: An Experimental Study.

Oryan A, Mohammadalipour A, Moshiri A, Tabandeh MR.
Annals of Plastic Surgery. 2016 Jan;77(1):37-46


Comparative Evaluation of Aloe Vera in the Management of Burn Wounds in Guinea Pigs.

Rodriguez-Bigas M, Cruz NI, Suarez A.
Plastic and Reconstructive Surgery. 1988 Mar;81(3):386-389.


Anti-inflammatory and wound healing activity of a growth substance in Aloe vera.

Davis RH, Donato JJ, Hartman GM, Haas RC.
Journal of the American Podiatric Medical Association. 1994 Feb;84(2):77-81.


Investigation of the anti-inflammatory potential of Aloe vera gel (97.5%) in the ultraviolet erythema test.

Reuter J, Jocher A, Stump J, Grossjohann B, Franke G, Schempp CM.
Skin Pharmacology and Physiology. 2008;21(2):106-10.


A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice.

Finberg MJ, Muntingh GL, van Rensburg CE.
Inflammopharmacology. 2015 Dec;23(6):337-41


Screening Methods Used to Determine the Anti-Microbial Properties of Aloe Vera Inner Gel.

Habeeb F, Shakir E, Bradbury F, et al.
Methods. 2007 Aug;42(4):315-320.


Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques

Dal'Belo, S.E., Rigo Gaspar, L. and Berardo Gonçalves Maia Campos, P.M.
Skin Research and Technology, 05 October 2006; 12: 241-246.

Additional studies related to aloe's benefits are available at the International Aloe Science Council website.