Those with acne tend to have skin cells that are abnormally “sticky” and, thus, the process of shedding dead skin cells is compromised. Instead of falling away, these dead cells have a tendency to clump together, blocking pores and causing a backup of sebum (oil) in the follicle.
Excess Sebum Production
Acne is often associated with enlarged sebaceous glands that produce higher quantities of sebum than is normal.
Prevalence of Acne Bacteria
Propionibacterium Acnes (P. acnes) is the bacteria responsible for acne. While it is present on the skin of nearly all healthy adults, that of some individuals is more hospitable to its presence.
Within the skin of all individuals, free radical damage causes a release of inflammatory chemicals, which are intended to repair this damage. In some individuals, however, the inflammation response is overly vigorous. This creates an environment that is perfectly suited for colonization of acne bacteria.